张葵花简历

1.基本情况

张葵花，女，教授， 高分子材料系主任，理学博士，嘉兴学院民建支部副主委，研究方向生物医用高分子材料及高吸水树脂材料。

2. 教育背景

2014-01至2014-12, 浙江大学，高分子科学与工程学系，国内访问学者

2007-09至2010-10，东华大学，高分子化学与物理，博士

2003-09至2006-07，华侨大学，高分子化学与物理，硕士

1987-09至1989-07，江西省抚州师范专科学校，化学教育

3. 工作经历

2006-07至至今，嘉兴学院，材料与纺织工程学院 教师

1998-10至2006-07，泉州师院化学系教师

1989-07至1998-10，江西资溪中学教师

4. 主要科研成果

主要课题

1. 浙江省自然科学基金委员会，一般项目，LY20C100003，促血管化高度仿生神经导管诱导神经再生研究，主持。

2. 嘉兴市公益计划项目，一般项目，2021AY10062, 多功能性丝素蛋白/壳聚糖纳米纤维仿生敷料关键技术研究，主持。

3. 国家自然科学基金委员会，面上项目，31271035， 双营养因子缓释型轴向取向纳米纤维神经导管诱导长距离神经再生的研究，参与。

4.浙江省创新团队项目子课题, 2010R50012-19，负载双因子取向纳米纤维用于神经导管的构建，主持。

5.国家自然科学基金委员会，面上项目，51073072，电活性仿生神经支架材料的研制和电活性评价体系的构建，参与。

6.浙江省自然科学基金委员会，一般项目，Y4100745，含神经生长因子的聚吡咯/蜘蛛丝蛋白电活性神经导管的构建，参与。

7. 浙江省教育厅课题, Y201122407，丝素蛋白基纳米纤维仿生支架用于周围神经修复的研究，主持。

8. 嘉兴市科技局项目，2010AY1089，控释型活性纳米纤维用于周围神经导管的研制，主持。

主要发表文章

1. Xinglu Zhou, Anlin Yin, Junlu Sheng, Jiayan Wang, Huifen Chen, Yun Fang, Kuihua Zhang. In situ deposition of nano Cu2O on electrospun chitosan nanofibrous scaffolds and their antimicrobial properties. Int. J. Biolog. Macromol. 2021, 191, 600–607.

2. Junjie Shen, Jiayan Wang, Xuanzhe Liu, Yi Sun, Anlin Yin, Yimin Chai, Kuihua Zhang,* Chunyang Wang,* and Xianyou Zheng* In Situ Prevascularization Strategy with Three-Dimensional Porous Conduits for Neural Tissue Engineering. ACS Appl. Mater. Interfaces 2021, 13, 50785−50801

3. 张葵花, 代正伟, 吴雯. 基于工程创新能力培养的高分子物理实验混合式教学改革研究-以嘉兴学院为例. 嘉兴学院学报,2021, 33, 140-144.

4. 张葵花.基于“核心知识点＋学习兴趣”培养的线上线下混合式教学研究

—以《功能高分子材料》课程为例. 功能高分子通报，2020， 8，86-91.

5. Chengwei Yang, Zhiyong Yan, Yuan Lian, Jiayan Wang, Kuihua Zhang*. Graphene oxide coated shell-core structured chitosan/PLLA nanofibrous scaffolds for wound dressing. Journal of Biomaterials Science, Polymer Edition, 2020, 31: 622–641.

6. Zexin Zheng, Kuihua Zhang*, Bo Wu, Haoyi Yang, Mengqi Wang, Tianhong Dong, Jiaying Zhang, Ying He Green electrospun nanocuprous oxide–poly(ethylene oxide)–silk fibroin composite nanofibrous scaffolds for antibacterial dressings. Journal of Applied Polymer Science, 2019, 136: 47730.

7. Jinxia Li, Kuihua Zhang *, Mengyi Zhang, Yu Fang, Xiaofeng Chu, Lu Xu. Fabrication of a fast-swelling superabsorbent resin by inverse suspension polymerization. Journal of Applied Polymer Science, 2018, 135: 46142.

8. Chunyang Wang#, Yachao Jia#, Weichao Yang, Cheng Zhang, Kuihua Zhang*, Yimin Chai*. Silk fibroin enhances peripheral nerve regeneration by improving vascularization within nerve conduits. Journal of Biomedical Materials Research Part A: 2018,106A: 2070–2077.

9. Kuihua Zhang*, Dianwu Huang, Zhiyong Yan, Chunyang Wang. Heparin/collagen encapsulating nerve growth factor multilayers coated aligned PLLA nanofibrous scaffolds for nerve tissue engineering, Journal of Biomedical Materials Research: Part A 2017, 105A: 1900-1910.

10. Kuihua Zhang, Honghao Zheng, Su Lang, Changyou Gao*. Aligned PLLA nanofibrous scaffolds coated with graphene oxide for promoting neural cell growth, Acta Biomaterialia, 2016, 37: 131-142.

11. Kuihua Zhang#, Chunyang Wang#, Cunyi Fan*, Xiumei Mo*. Aligned SF/P(LLA-CL) blended nanofibers encapsulating nerve growth factor for peripheral nerve regeneration, Journal of Biomedical Materials Research: Part A, 2014, 102A: 2680-2691.

12. Kuihua Zhang, Jinglei Wu, Chen Huang, Xiumei Mo*. Fabrication of silk fibroin/P(LLA-CL) aligned nanofibrous scaffolds for nerve tissue engineering, Macromolecular Materials and Engineering, 2013, 298: 565-574.

13. Kuihua Zhang, Linpeng Fan, Zhiyong Yan, Qiaozhen Yu, Xiumei Mo*. Electrospun biomimic nanofibrous scaffolds of silk fibroin/hyaluronic acid for tissue engineering. Journal of Biomaterials Science, 2012, 23:1185-1198

14. Kuihua Zhang*, Qing Ye, Zhiyong Yan. Influence of post-treatment with 75% (v/v) ethanol vapor on the properties of SF/P(LLA-CL) nanofibrous scaffolds. International Journal of Molecular Sciences, 2012, 13: 2036-2047.

15. Chunyang Wang#, Kuihua Zhang# , Cunyi Fan , Xiumei Mo, Hongjiang Ruan, Fengfeng Li. Aligned natural–synthetic polyblend nanofibers for peripheral nerve regeneration. Acta Bio materialia, 2011, 7: 634–643.

16. Kuihua Zhang, Anlin Yin, Chen Huang, Chunyang Wang, Xiumei Mo*, Salem S. Al-Deya, Mohamed El-Newehy. Degradation of electrospun SF/P(LLA-CL) blended nanofibrous scaffolds in vitro. Polymer Degradation and Stability, 2011, 96: 2266-2275.

17. Kuihua Zhang, Yongfang Qian, Hongsheng Wang, Linpeng Fan, Chen Huang , Xiumei Mo*. Electrospun silk fibroin–hydroxybutyl chitosan nanofibrous scaffolds to biomimic extracellular matrix. Journal of Biomaterials Science, 2011, 22: 1069-1082.

18. Kuihua Zhang*, Qiazhen Yu, Xiumei Mo. Fabrication and intermolecular interactions of silk fibroin/hydroxybutyl chitosan blended nanofibers. International Journal of Molecular Sciences. 2011, 12: 2187-2199

19. Kuihua Zhang, Xiumei Mo*, Chen Huang, Chuanglong He, Hongsheng Wang. Electrospun scaffolds from silk fibroin and their cellular compatibility. Journal of Biomedical Materials Research: Part A, 2010, 93A: 976–983.

20. Kuihua Zhang, Hongsheng Wang, Chen Huang, Yan Su, Xiumei Mo*, Yoshito Ikada. Fabrication of silk fibroin blended P(LLA-CL) nanofibrous scaffolds for tissue engineering Journal of Biomedical Materials Research: Part A, 2010, 93A: 984–993.

21. Kuihua Zhang, Yongfang Qian, Hongsheng Wang, Linpeng Fan, Chen Huang, Anlin Yin, Xiumei Mo*. Genipin-crosslinked silk fibroin/hydroxybutyl chitosan nanofibrous scaffolds for tissue-engineering application. Journal of Biomedical Materials Research: Part A: 2010, 95A: 870–881.

授权专利

1. 张葵花,  颜志勇, 连媛, 李喆, 姚勇波, 生俊露. 含氧化亚铜/丝素蛋白复合物及其制备方法，ZL201910312191.8.

1. 张葵花，颜志勇，张梦怡，抗菌纳米纤维及其制备方法， ZL201611232870.7.

2. 张葵花, 负载维生素C的丝素蛋白/透明质酸复合纳米纤维的制备方法, ZL201310301928.9.

3. 马国林, 张葵花, 刘健, 阮玉林,一种电缆或光缆用高吸水树脂的制备方法, ZL201210156666.7.

4. 莫秀梅，张葵花，邱立军，王红声，丝素蛋白/P(LLA-CL)复合纳米纤维组织修复的制备方法，中国，ZL200910045769.4.

获奖

获嘉兴市自然科学一等奖，中国有色金属工业科学技术奖三等奖 嘉兴学院优秀教师